Bronopol does not belong to the "formaldehyde release" fungicide


Bronopol is a class of high-efficiency, broad-spectrum preservatives with the following distinct advantages:


Bronopol at a concentration of ppm can effectively kill bacteria


Multi-bacterial mechanism, broad-spectrum killing of Gram-positive bacteria, Gram-negative bacteria, yeasts, molds commonly found in the environment


It has special control effect on pseudomonas bacteria commonly found in water, and is a powerful supplement to KATHON preservatives.


Since the 1970s, Bropol has been widely used in the preservation of washing industry products.


In some cases, bronopol releases a small amount of formaldehyde due to hydrolysis, but the amount of formaldehyde released in Bropol is much lower than the dose required for bactericidal action. Therefore, Broll is not really meaningful. Preservatives for "formaldehyde release". The United States and the relevant EU regulations have reached an agreement on this. As early as the EU Working Group meeting in January 2007, all participants reached a consensus that Bolpo's bactericidal ability is independent of formaldehyde, which relies mainly on the Bolopol molecule itself and the thiol group in the microbial cell structure. The group interaction is related to the formation of oxygen free radical sterilization. According to this mechanism of action, Brovopol is not a "formaldehyde-releasing body" fungicide. US EPA (Environmental


Protection Agency also claims that Bronopol is largely refrained from formaldehyde sterilization.

In fact, Broll is not a "formaldehyde-releasing body" fungicide, and the amount of formaldehyde released is very small. Choosing the right test method is critical to accurately measuring the amount of formaldehyde released by Bropol. At present, the formaldehyde content of acetylacetone spectrophotometry is widely used in the industry. The method is based on the selective reaction of formaldehyde with Nash's reagent (acetylacetone) in the presence of ammonium acetate to form yellow 2,6-dimethyl-3, 5-diacetyl-1,4 dihydropyridine. The formaldehyde content is measured in terms of spectrophotometry.

Does the trace amount of formaldehyde produced by Bropol affect product safety due to hydrolysis?

In fact, formaldehyde exists in humans and in a large number of common foods, as shown in Table 8. The hydrolysis of Brobopol to form less than 1 ppm of formaldehyde is lower than the formaldehyde content of these common foods. At the same time, China's "Hygienic Standards for Cosmetics (2007)" stipulates that Brovpol's limited preservatives for cosmetics (the amount of additives should be less than 0.1%, while avoiding the formation of nitrosamines), also proved that under the correct use conditions Bropol is used for the safety of liquid laundry products.

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